Subject :- Shilpa Medicare announces successful outcome of Phase 3 studies of SMLNUD07 – NorUDCA

Shilpa Medicare has achieved a significant milestone with the successful completion of Phase 3 clinical trials for its novel product, SMLNUD07 – Nor-Ursodeoxycholic Acid (NorUDCA) tablets, a potential game-changer in the treatment of Nonalcoholic Fatty Liver Disease (NAFLD). This trial, which was a multicentric, placebo-controlled, double-blinded study, involved 165 NAFLD patients across India, providing a robust and statistically reliable dataset. The study demonstrated that NorUDCA was well tolerated at a dosage of 1500 mg per day over a 24-week period, with no serious adverse events reported. Efficacy results were promising, with patients experiencing at least a one-stage reduction in liver fibrosis, as measured by the USFDA-approved Fibroscan technique. Additionally, a significant reduction in hepatic fat accumulation was observed, evaluated using the CAP scoring technique. The study also reported a significant normalization of Alanine Aminotransferase (ALT) levels, indicating improved liver function. These findings suggest that NorUDCA could become a new standard of care for NAFLD, offering significant improvements in liver function and a holistic approach to treatment by addressing multiple disease outcomes.

Shilpa Medicare plans to submit these results to the Central Drugs Standard Control Organization (CDSCO) in India to seek marketing authorization. NorUDCA stands out as a first-in-class treatment option in India, with notable advantages over conventional Ursodeoxycholic Acid (UDCA), including enhanced choleretic effects, resistance to amidation, anti-inflammatory properties, and a reduction in fibrosis. NAFLD is the most prevalent liver disease globally, affecting approximately 25% of the world’s population, which translates to about 1.2 billion people. In India alone, around 188 million people are affected. If untreated, NAFLD can progress to nonalcoholic steatohepatitis (NASH), which can have severe and potentially fatal implications

Good company to invest for long term…around 67% of there occupancy is with large MNCs…further, with rate cuts cycle on the horizon, the IT sector and startups will see rise in order flows and funding flows in the coming years…this will help generate greater demand for coworking space …

In the below tracker, I have started tracking important company goals for WTI. These goals are referred to as ‘monitorables’ in the tracker.I will update this document regularly to reflect the current status of these goals.

Here’s a snapshot of what the tracker includes:

• Company Ticker: For identifying the company
• Monitorable Description: Description of the goal or metric being tracked
• Date of Announcement: When the monitorable was announced
• Deadline: Target date for achieving the monitorable
• Status: Current progress (e.g., Not Fulfilled, Pending)
• Verification Link: A link to see where I got the information about the goal.

I hope this information makes it easier to observe how well companies are progressing towards their stated goals.

Screenshot of the tracker below:

Full tracker attached below:
Tracking Company Monitorables-35.xlsx (146.6 KB)

Post Script: DM if you want me to track the monitorables for any specific company.

Started doing some digging around publicly disclosed exposure of IDFC First Bank, and I was able to find one exposure to Adani Enterprises of INR 350 Crores.

Here is the list of companies checked for via zaubacorp.com

• Adani Enterprises: 350 Crores – There’s an invalid closure date -0001-11-30, so this could be still active?
• Adani Total Gas: 150 Crores – Shows closed on 2017-08-21 so this was previous management
• Penna cement: None (Acquired by Adani / Ambuja in Jun 2024)
• Adani Trade And Logistics LLP: None
• DIRK TRADE AND LOGISTICS LLP: None
• AMBUJA CEMENTS LIMITED: None including its related establishments (Rajasthan, Gujarat, etc.)
• ADANI POWER LIMITED: None
• ADANI CEMENT INDUSTRIES LIMITED: None
• ADANI ENERGY SOLUTIONS LIMITED: None
• ADANI PORTS AND SPECIAL ECONOMIC ZONE LIMITED: None
• MUNDRA SPECIAL ECONOMIC ZONE LIMITED: None
• ADANI LOGISTICS LIMITED: None
• ADANI ELECTRICITY MUMBAI LIMITED: None
• ADANI RESOURCES PRIVATE LIMITED: None
• ADANI AEROSPACE AND DEFENCE LIMITED: None
• ADANI GREEN ENERGY LIMITED: None
• ADANI TOTAL PRIVATE LIMITED: None
• ADANI INFRA (INDIA) LIMITED: None
• ADANI KRISHNAPATNAM PORT LIMITED: None
• MANGALURU INTERNATIONAL AIRPORT LIMITED: None
• ADANI AGRI LOGISTICS (MANSA) LIMITED: None
• ADANI AGRI LOGISTICS (HOSHANGABAD) LIMITED: None
• ADANI AGRI LOGISTICS (DAHOD) LIMITED: None
• MANCHERIAL REPALLEWADA ROAD PRIVATE LIMITED: None
• GUWAHATI INTERNATIONAL AIRPORT LIMITED: None
• ADANI GLOBAL (INDIA) PRIVATE LIMITED: None

Depending on what people believe about Adani Group, I often wonder, when someday it unwinds, what would happen to Indian banking/NBFC industry given the overall exposure to one group (₹88,100 Crores – USD 10 billion)

Company has announced the acquisition of contracts of Rs. 20.07
Crores

https://nsearchives.nseindia.com/corporate/PRLIND_21082024110018_PRLPressRelease21082024.pdf