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Suven Life Sciences initiates phase 2A trial of SUVN-502 in USA in Alzheimer’s Disease

This trial is designed to evaluate the safety, tolerability, pharmacokinetics and efficacy of SUVN-502 for the treatment of moderate Alzheimer’s Disease
Suven Life Sciences, a clinical stage biopharmaceutical company developing novel medicines to treat life-threatening Central Nervous System (CNS) disorders, has initiated dose administration of the first patient in a Phase 2A clinical trial of SUVN-502, a 5HT6 antagonist in patients with moderate Alzheimer’s Disease (AD). The clinical development program being executed through Suven, Inc., a Delaware Company in USA, wholly owned subsidiary of Suven Life Sciences.

This trial is designed to evaluate the safety, tolerability, pharmacokinetics and efficacy of SUVN-502 for the treatment of moderate Alzheimer’s Disease (AD).

This trial is expected to enroll 537 patients and the primary objective of the study is to evaluate the efficacy of a serotonin receptor subtype 6 (5-HT6) antagonist, SUVN-502, at daily doses of 50 mg or 100 mg compared to placebo, as adjunct treatment in subjects with moderate Alzheimer’s disease (Mini-Mental State Examination [MMSE] score of 12 to 20) currently treated with the acetylcholinesterase inhibitor, Donepezil Hydrochloride (HCI) and the N-methyl-D-aspartic acid (NMDA) antagonist, MemantineHCI. Efficacy will be assessed by the 11-item Alzheimer’s Disease Assessment Scale for Cognitive Behavior (ADAScog-11) after 26 weeks of treatment. The trial is likely to complete by end of second quarter 2017, subject to the achievement of estimated 12 months’ enrollment goal in USA.

Secondary objectives are to further evaluate the efficacy of these treatments using scales i.e. Clinical Dementia Rating (CDR) Scale, Sum of Boxes (CDR-SB), MMSE, Alzheimer’s Disease Co-operative Study Activity of Daily Living (ADCS-ADL), Neuropsychiatric Inventory (NPI) 12 item and Cornell Scale for Depression and Dementia (C-SDD) and this study is being coordinated by Dr. Jeffrey Cummings, MD, Director, Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV, USA.

Suven Life Science is a biopharmaceutical company focused on discovering, developing and commercializing novel pharmaceutical products, which are first in class or best in class CNS therapies through the use of GPCR targets.
source : ventura

 

Nse MOTHERSUMI 10 lacs @ 276.90 value 27.73 crs (Bulk / Block Deals)

 

Idea Cellular unveils 3G services in Delhi

The company will soon launch 3G services in Kolkata

Idea Cellular, one of the biggest cellular carrier of the country has unveiled third generation (3G) services in Delhi on 900 Mhz band with the support of 2,500 3G cell sites and 5,000 upgraded 2G cell sites. With this launched, the company's 3G customers in Delhi will have a better experience, while accessing services like video telephony, mobile TV, video on demand, music downloads, online gaming, amongst many others. The company will soon launch better quality 3G services in Kolkata.

Idea Cellular is an Aditya Birla Group Company, India's first truly multinational corporation. Idea is a pan-India integrated GSM operator offering 2G and 3G services, and has its own NLD and ILD operations, and ISP license. Idea has won spectrum to launch 4G services across 10 key markets and has initiated multiple steps towards introduction of 4G LTE services on 1800 MHz, in a phased manner from calendar year 2016 onwards.
source : ventura

 

Nse SUPREMEIND 4.99 lacs @ 660 value 32.98 crs (Bulk / Block Deals)

 

Apollo Tyres resumes operations at its manufacturing plant in Chennai

The firm would be able to assess the insurance loss in due course, once full normalcy is restored
Apollo Tyres has resumed operations at its manufacturing plant located at Oragadam near Chennai. The company only had production loss/consequential loss of profit which is not significant. So far, the company has lost 10 shifts production (1,500 MT approximately). The firm would be able to assess the insurance loss in due course, once full normalcy is restored.

Apollo Tyres had suspended operations at the respective plant due to flooding caused by the heaviest rainfall in Chennai in over a century.

Apollo Tyres produces the entire range of automotive tyres for ultra and high speed passenger cars, truck and bus, farm, off-the-road, industrial and specialty applications like mining, retreaded tyres and retreading material. These are produced across Apollo’s eight manufacturing locations in India, Netherlands and Southern Africa.
source : ventura

 

Nse GSPL 6.50 lacs @ 132.60 value 8.61 crs (Bulk / Block Deals)

 

Vijaya Bank plans to reduce net NPA under 2%: Report

The bank’s gross NPA for the July-September quarter of the current fiscal increased to 3.98%
Vijaya Bank, the Karnataka-based bank is reportedly planning to reduce its net non-performing assets (NPAs) to below 2% of total advances by the end of the current financial year. All regional managers and their teams are approaching customers either for upgradation or for one-time settlement. The bank has also initiated measures such as cajoling, handholding, restructuring and refinancing, wherever required.

The bank’s gross NPA for the July-September quarter of the current fiscal increased to 3.98%, as compared to 2.85% in the same quarter of the previous year. Besides, bank’s Net NPA stood at 2.84% in Q2FY16.

Vijaya Bank offers various products and services specific to various segments such as it has saving accounts for children, scheme for women clientele, credit facilities to minority communities like Zoroastrians, Buddhists are among others.
source : ventura

 

Siemens wins order worth Rs 377 crore from Diesel Locomotive Works, Varanasi

The scope of work for the project involves supply of 1890 Traction Motors for 4500 HP Diesel Electric Locomotives
Siemens has won a crucial order approximately worth Rs 377 crore from Indian Railways’ Diesel Locomotive Works (DLW), Varanasi. The scope of work for the project involves supply of 1890 Traction Motors for 4500 HP Diesel Electric Locomotives. The Traction Motors will be produced at Kalwa Factory of Siemens.

Siemens is a technology powerhouse that has stood for engineering excellence, innovation, quality and reliability. The company focuses on the areas of electrification, automation and digitalization. It is one of the leading producers of energy-efficient, resource-saving technologies; combined cycle turbines for power generation; and power transmission solutions
source : ventura

 

Anuh Pharma gets GMP certificate from COFEPRIS for two products

These products are Chloramphenicol and Chloramphenicol Palmitate
Anuh Pharma has received Good Manufacturing Practice (GMP) certificate from COFEPRIS (Health Authority of Mexico) for two products. These products are Chloramphenicol and Chloramphenicol Palmitate.

Anuh Pharma is one of the leading manufacturers of Active Pharmaceutical Ingredients (APIs). The company is part of the SK Group, which has evolved as a leading importer, exporter, distributor and manufacturer of bulk drugs, chemicals and pharmaceutical formulations.
source : ventura

 

Nse ULTRACEMCO 44 k @ 2882 value 12.93 crs (Bulk /Block Deals)

 

Nifty stocks top looser : ITC Price Rs. 315.50 , - 6.09 %

 

Source : BSEINDIA :

Advance : 1393
Decline : 1171
Unchanged : 164
Total : 2728

 

Ashapura Intimates to open EBO store in Pune

The company will inaugurate this unit on December 08, 2015
Ashapura Intimates Fashion is all set to inaugurate EBO store at Unit No S-36C, Second Floor, Phoenix Marketcity, Viman Nagar Road in Pune on December 08, 2015.

Ashapura Intimates Fashion is engaged in the business of designing, branding, marketing and retailing of intimate garments through a well developed & wide distribution network and undertakes sales through organized retail chains and own outlets.
source : ventura

 

Goldman Sachs thinks oil prices could fall another 50% as the market spends another year sorting itself out

NEW YORK: The oil market is out of whack and Goldman Sachs doesn't see this situation sorting itself out for another year. In a note to clients on Friday following Opec's latest output announcement, Goldman's Damien Courvalin wrote the oil market's supply and demand balance won't be restored until Q4 of 2016 at the earliest.

On Friday, Opec — the 13-member oil cartel — announced it will look to maintain its current rate of production at around 31.5 million bpd. Goldman expects Opec ..

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Adani plans ports to cover India’s coastline & enter foreign shores

THIRUVANANTHAPURAM: The $10-billion Adani Group is stringing together a Sagar Mala or necklace of ports dotting India's coastline, said Karan Adani, soon after the ground-breaking ceremony at Vizhinjam, which will form one of these facilities when it's ready. In addition to this, the company is also looking to establish ports in at least four countries close to India to create synergistic linkages with Adani's Indian assets, he said. In addition to the nine Adani ports in India, including Vizhi ..

"We have three missing pieces left — Maharashtra, Karnataka and Andhra Pradesh," said Adani, 27, executive director of Adani Ports and Special Economic Zone (APSEZ) in Thiruvananthapuram, the Kerala state capital. "We are actively scouting, greenfield and brownfield sites."

APSEZ, the group's flagship company, is now India's largest private sector port operator with a significant presence in Gujarat, Goa, Tamil Nadu and Odisha.

"We'll look to go international. We are actively ..

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Godrej Properties sells 300 apartments within a week

MUMBAI: Godrej Properties, the real estate development arm of the Godrej Group, has sold 300 apartments within one week at its newly launched project The Trees at Mumbai's Vikhroli suburb, the company said in a statement.

This represents over 80 per cent of the 374 apartments the developer had opened for sale in the first phase of this project. The value of apartments sold is in excess of 700 crores making this Godrej Properties' most successful ever launch in terms of value of real es ..

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Mutual Funds see Rs 31,000 crore outflow in November

NEW DELHI: Investors pulled out more than Rs 31,000 crore from various mutual fund schemes in November, with liquid and money markets contributing the most to the outflow.

This follows an inflow of about Rs 1.35 lakh crore into mutual fund (MF) products in the preceding month.

According to data from the Association of Mutual Funds in India ( Amfi), investors withdrew a sum of Rs 31,196 crore from MF schemes last month.

Industry insiders said mutual funds saw an outflo ..

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Flood disrupts production operations at Manali Petrochemicals’ both plants

The plant operations are expected to recommence shortly in a phased manner subject to resumption of normalcy in power supply, material movements, etc
Manali Petrochemicals’ production at its both Plants remains affected since December 02, 2015 due to flooding and the resultant power disruptions. The plant operations are expected to recommence shortly in a phased manner subject to resumption of normalcy in power supply, material movements, etc. Consequently the overall operations for the quarter and the year will be impacted significantly.

Manali Petrochemicals (MPL) is a leader in the production and marketing of Propylene Oxide, Propylene Glycols and Polyols in India. The Company operates two grassroot production facilities at Manali to manufacture Propylene oxide (PO), Propylene Glycol (PG) and Polyols. It markets its Polyols with isocyanates sourced indigenously as well as imported from Japan and China and the pre-polymers produced at MPL in meeting the demand of polyurethane industry in India.
source : Ventura

 

Nse IBULHSGFIN 2.34 lacs @ 699 value 16.41 crs (Block / Bulk Deals )

 

Titan Company informs about joint venture with Montblanc Services B.V

Titan Company has informed about Joint Venture with Montblanc Services B.V, Netherlands - Continuous Disclosure.

The above information is a part of company’s filings submitted to BSE
source : ventura